Patrice O’Neal has passed away from complications related to a serious stroke he suffered in late October. He was 41.

Opie of the Opie and Anthony show first reported the death by Tweeting: “Yes it’s true that our pal Patrice O’Neal has passed away. The funniest and best thinker I’ve ever known PERIOD.”

O’Neal most recently worked the Charlie Sheen Roast on Comedy Central. He also appeared on  Chappelle’s Show and The Office in addition to Tough Crowd with Colin Quinn.